The study of the process for isolation, purification, structure elucidation, and bioactivities of some compounds from the leaves of Northern “Chay” (Artocarpus tonkinensis A.Chev. ex Gagnep., Moraceae) was carried out. The study explored anti-oxygenase and anti-cancer activities of three extracts n-hexane (EtOAc; BuOH) and tested immunosuppressive activity by lymphocyte transformation test. Bioactivity-guided fractionation of the n-butanol extract from the leaves of Artocarpus tonkinensis A.Chev. ex Gagnep. led to the isolation of two auronol glucosides named maesopsin 4-O-b-D-glucopyranoside and the new alphitonin-4-O-b-D-glucopyranoside. Their structures were determined on the basis of MS and NMR spectroscopic data.
Nguyen The Anh, Ho Ngoc ANh, Trinh Thi Thuy, Tran Van Sung
Institute of Chemistry, VAST
Tran Minh Hoi
(Proceedings of 3rd National Scientific Conference on Ecology and Biological Resources, Hanoi 22th October 2009 - IEBR)